ProFILER

This database program describes itself as easy to use thanks to Mousetext and supporting mouse input, use of RAM disks, 3.5" disk drives and hard drives, all easily found through easy to use open and save dialogues that don't require memorising file paths and prefixes, automatic time and date stamping, and easy interface with Appleworks, and word processors such as Word Juggler, Word Perfect, Apple Writer II.

I'm guessing it's not got relational database capabilities, but it does look like the most easy to use powerful database program for 8-bit Apple II's. It even comes with tutorial slide shows to help you get started and know the better features of the software.

Currently, the version held on archive is v4.0.9.